He got famous almost in late 1990's after acting in 2 Days in the Valley, Mighty Joe Young, The Devil's Advocate and The Cider House Rules.
She has won most of her award for acting in "Monster" and she won the Academy Awards for it in 2003.
At the moment she's playing in 4 different projects:
2012Mad Max: Fury Road (pre-production)
Furiosa
Furiosa
Charlize Theron winning Oscar in 2003
Charlize Theron in Martini Commercial in 1993